PRKCQ

GENE INFORMATION

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Gene name

PRKCQ

Synonyms

Description

protein kinase C, theta (HGNC Symbol)

Entrez gene summary

Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role. The protein encoded by this gene is one of the PKC family members. It is a calcium-independent and phospholipid-dependent protein kinase. This kinase is important for T-cell activation. It is required for the activation of the transcription factors NF-kappaB and AP-1, and may link the T cell receptor (TCR) signaling complex to the activation of the transcription factors. [provided by RefSeq, Jul 2008]

Chromosome

10 (Chromosome progress)

Cytoband

p14

Chromosome location (bp)

6469105 - 6622263

Ensembl

ENSG00000065675 (version 73.37)

Entrez gene

5588

UniProt

Q04759 (UniProt - Evidence at protein level)

neXtProt

NX_Q04759

Antibodypedia

PRKCQ antibodies
 

PROTEIN VIEW

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PRKCQ-001
 
PRKCQ-201
 
PRKCQ-202
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PRKCQ-001 ENSP00000263125
ENST00000263125
Q04759
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Show » Show » 706 81.9 No 0
PRKCQ-201 ENSP00000380361
ENST00000397176
Q04759
Show all »
Show » Show » 643 74.3 No 0
PRKCQ-202 ENSP00000441752
ENST00000539722
B4DF52
Show all »
Show » Show » 581 67.6 No 0