NEO1

GENE INFORMATION

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Gene name

NEO1 (HGNC Symbol)

Synonyms

HsT17534, IGDCC2, NGN

Description

neogenin 1 (HGNC Symbol)

Entrez gene summary

This gene encodes a cell surface protein that is a member of the immunoglobulin superfamily. The encoded protein consists of four N-terminal immunoglobulin-like domains, six fibronectin type III domains, a transmembrane domain and a C-terminal internal domain that shares homology with the tumor suppressor candidate gene DCC. This protein may be involved in cell growth and differentiation and in cell-cell adhesion. Defects in this gene are associated with cell proliferation in certain cancers. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010]

Chromosome

15 (Chromosome progress)

Cytoband

q24.1

Chromosome location (bp)

73344051 - 73597547

Ensembl

ENSG00000067141 (version 73.37)

Entrez gene

4756

UniProt

Q92859 (UniProt - Evidence at protein level)

neXtProt

NX_Q92859

Antibodypedia

NEO1 antibodies
 

PROTEIN VIEW

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NEO1-001
 
NEO1-002
 
NEO1-003
 
NEO1-004
 
NEO1-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

NEO1-001 ENSP00000341198
ENST00000339362
Q92859
Show all »
Show » Show » 1461 160 Yes 1
NEO1-002 ENSP00000454024
ENST00000560328
Q59FP8
Show all »
Show » Show » 1130 124 No 1
NEO1-003 ENSP00000453317
ENST00000560262
Q92859
Show all »
Show » Show » 1408 154.3 Yes 1
NEO1-004 ENSP00000453200
ENST00000558964
Q92859
Show all »
Show » Show » 1450 158.8 Yes 1
NEO1-201 ENSP00000261908
ENST00000261908
Q92859
Show all »
Show » Show » 1461 160 Yes 1