VPS35

GENE INFORMATION

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Gene name

VPS35 (HGNC Symbol)

Synonyms

FLJ10752, MEM3, PARK17

Description

Vacuolar protein sorting 35 homolog (S. cerevisiae) (HGNC Symbol)

Entrez gene summary

This gene belongs to a group of vacuolar protein sorting (VPS) genes. The encoded protein is a component of a large multimeric complex, termed the retromer complex, involved in retrograde transport of proteins from endosomes to the trans-Golgi network. The close structural similarity between the yeast and human proteins that make up this complex suggests a similarity in function. Expression studies in yeast and mammalian cells indicate that this protein interacts directly with VPS35, which serves as the core of the retromer complex. [provided by RefSeq, Jul 2008]

Chromosome

16

Cytoband

q11.2

Chromosome location (bp)

46690054 - 46723430

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000069329 (version 75.37)

Entrez gene

55737

UniProt

Q96QK1 (UniProt - Evidence at protein level)

neXtProt

NX_Q96QK1

Antibodypedia

VPS35 antibodies
 

PROTEIN VIEW

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VPS35-001
 
VPS35-002
 
VPS35-005
 
VPS35-008
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

VPS35-001 ENSP00000299138
ENST00000299138
Q96QK1
Show all »
Show » Show » 796 91.7 No 0
VPS35-002 ENSP00000456274
ENST00000568784
H3BRJ7
Show all »
Show » 48 5 No 0
VPS35-005 ENSP00000461423
ENST00000561713
I3L4P4
Show all »
Show » 47 5.5 No 0
VPS35-008 ENSP00000461469
ENST00000568612
I3L4S0
Show all »
Show » 41 4.7 No 0