BCL3

GENE INFORMATION

? »

Gene name

BCL3 (HGNC Symbol)

Synonyms

BCL4, D19S37

Description

B-cell CLL/lymphoma 3 (HGNC Symbol)

Entrez gene summary

microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

Chromosome

19

Cytoband

q13.32

Chromosome location (bp)

45250962 - 45263301

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000069399 (version 75.37)

Entrez gene

102465879

UniProt

P20749 (UniProt - Evidence at protein level)

neXtProt

NX_P20749

Antibodypedia

BCL3 antibodies
 

PROTEIN VIEW

? »
 
 
 
BCL3-001
 
BCL3-005
 
 
 
 
 

PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

BCL3-001 ENSP00000164227
ENST00000164227
P20749
Show all »
Show » Show » 454 47.6 No 0
BCL3-005 ENSP00000393731
ENST00000444487
Show » Show » 308 32.4 No 0