BCL3

GENE INFORMATION

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Gene name

BCL3 (HGNC Symbol)

Synonyms

BCL4, D19S37

Description

B-cell CLL/lymphoma 3 (HGNC Symbol)

Entrez gene summary

This gene is a proto-oncogene candidate. It is identified by its translocation into the immunoglobulin alpha-locus in some cases of B-cell leukemia. The protein encoded by this gene contains seven ankyrin repeats, which are most closely related to those found in I kappa B proteins. This protein functions as a transcriptional co-activator that activates through its association with NF-kappa B homodimers. The expression of this gene can be induced by NF-kappa B, which forms a part of the autoregulatory loop that controls the nuclear residence of p50 NF-kappa B. [provided by RefSeq, Jul 2008]

Chromosome

19 (Chromosome progress)

Cytoband

q13.32

Chromosome location (bp)

45250962 - 45263301

Ensembl

ENSG00000069399 (version 73.37)

Entrez gene

602

UniProt

P20749 (UniProt - Evidence at protein level)

neXtProt

NX_P20749

Antibodypedia

BCL3 antibodies
 

PROTEIN VIEW

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BCL3-001
 
BCL3-005
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

BCL3-001 ENSP00000164227
ENST00000164227
P20749
Show all »
Show » Show » 454 47.6 No 0
BCL3-005 ENSP00000393731
ENST00000444487
Show » Show » 308 32.4 No 0