ABCC9

GENE INFORMATION

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Gene name

ABCC9 (HGNC Symbol)

Synonyms

CMD1O, SUR2

Description

ATP-binding cassette, sub-family C (CFTR/MRP), member 9 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein is thought to form ATP-sensitive potassium channels in cardiac, skeletal, and vascular and non-vascular smooth muscle. Protein structure suggests a role as the drug-binding channel-modulating subunit of the extra-pancreatic ATP-sensitive potassium channels. Mutations in this gene are associated with cardiomyopathy dilated type 1O. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2011]

Chromosome

12 (Chromosome progress)

Cytoband

p12.1

Chromosome location (bp)

21950335 - 22094336

Ensembl

ENSG00000069431 (version 73.37)

Entrez gene

10060

UniProt

O60706 (UniProt - Evidence at protein level)

neXtProt

NX_O60706

Antibodypedia

ABCC9 antibodies
 

PROTEIN VIEW

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ABCC9-001
 
ABCC9-002
 
ABCC9-003
 
ABCC9-004
 
ABCC9-005
 
ABCC9-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ABCC9-001 ENSP00000261200
ENST00000261200
O60706
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Show » Show » 1549 174.4 No >9
ABCC9-002 ENSP00000261201
ENST00000261201
O60706
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Show » Show » 1549 174.2 No >9
ABCC9-003 ENSP00000440521
ENST00000544039
H0YFV4
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Show » Show » 1176 131.6 No >9
ABCC9-004 ENSP00000442604
ENST00000538350
G3V1N6
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Show » Show » 170 19.2 No 3
ABCC9-005 ENSP00000317518
ENST00000326684
Q8N4N7
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Show » Show » 149 17 No 3
ABCC9-201 ENSP00000261202
ENST00000345162
K4DI86
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Show » Show » 1513 169.9 No >9