DRD4

GENE INFORMATION

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Gene name

DRD4

Synonyms

Description

dopamine receptor D4 (HGNC Symbol)

Entrez gene summary

This gene encodes the D4 subtype of the dopamine receptor. The D4 subtype is a G-protein coupled receptor which inhibits adenylyl cyclase. It is a target for drugs which treat schizophrenia and Parkinson disease. Mutations in this gene have been associated with various behavioral phenotypes, including autonomic nervous system dysfunction, attention deficit/hyperactivity disorder, and the personality trait of novelty seeking. This gene contains a polymorphic number (2-10 copies) of tandem 48 nt repeats; the sequence shown contains four repeats. [provided by RefSeq, Jul 2008]

Chromosome

11 (Chromosome progress)

Cytoband

p15.5

Chromosome location (bp)

637293 - 640706

Ensembl

ENSG00000069696 (version 73.37)

Entrez gene

1815

UniProt

P21917 (UniProt - Evidence at protein level)

neXtProt

NX_P21917

Antibodypedia

DRD4 antibodies
 

PROTEIN VIEW

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DRD4-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

DRD4-001 ENSP00000176183
ENST00000176183
P21917
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