TGFBR3

GENE INFORMATION

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Gene name

TGFBR3 (HGNC Symbol)

Synonyms

betaglycan, BGCAN

Description

transforming growth factor, beta receptor III (HGNC Symbol)

Entrez gene summary

This locus encodes the transforming growth factor (TGF)-beta type III receptor. The encoded receptor is a membrane proteoglycan that often functions as a co-receptor with other TGF-beta receptor superfamily members. Ectodomain shedding produces soluble TGFBR3, which may inhibit TGFB signaling. Decreased expression of this receptor has been observed in various cancers. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.[provided by RefSeq, Sep 2010]

Chromosome

1 (Chromosome progress)

Cytoband

p22.1

Chromosome location (bp)

92145902 - 92371892

Ensembl

ENSG00000069702 (version 73.37)

Entrez gene

7049

UniProt

Q03167 (UniProt - Evidence at protein level)

neXtProt

NX_Q03167

Antibodypedia

TGFBR3 antibodies
 

PROTEIN VIEW

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TGFBR3-001
 
TGFBR3-002
 
TGFBR3-006
 
TGFBR3-007
 
TGFBR3-008
 
TGFBR3-009
 
TGFBR3-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

TGFBR3-001 ENSP00000359426
ENST00000370399
Q03167
Show all »
Show » Show » 850 93.4 Yes 1
TGFBR3-002 ENSP00000432638
ENST00000465892
Q03167
Show all »
Show » Show » 850 93.4 Yes 1
TGFBR3-006 ENSP00000436127
ENST00000525962
Q03167
Show all »
Show » Show » 851 93.5 Yes 1
TGFBR3-007 ENSP00000433477
ENST00000533089
E9PKY4
Show all »
Show » 89 9.3 Yes 0
TGFBR3-008 ENSP00000434994
ENST00000532540
E9PMG7
Show all »
Show » 49 5.3 Yes 0
TGFBR3-009 ENSP00000395975
ENST00000417833
E9PAW7
Show all »
Show » 35 3.5 Yes 0
TGFBR3-201 ENSP00000212355
ENST00000212355
Q03167
Show all »
Show » Show » 851 93.5 Yes 1