ATP1B3

GENE INFORMATION

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Gene name

ATP1B3 (HGNC Symbol)

Synonyms

CD298, FLJ29027

Description

ATPase, Na+/K+ transporting, beta 3 polypeptide (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene belongs to the family of Na+/K+ and H+/K+ ATPases beta chain proteins, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane. The glycoprotein subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes a beta 3 subunit. This gene encodes a beta 3 subunit. A pseudogene exists for this gene, and it is located on chromosome 2. [provided by RefSeq, Jul 2008]

Chromosome

3 (Chromosome progress)

Cytoband

q23

Chromosome location (bp)

141594966 - 141645356

Ensembl

ENSG00000069849 (version 73.37)

Entrez gene

483

UniProt

P54709 (UniProt - Evidence at protein level)

neXtProt

NX_P54709

Antibodypedia

ATP1B3 antibodies
 

PROTEIN VIEW

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ATP1B3-001
 
ATP1B3-002
 
ATP1B3-003
 
ATP1B3-004
 
ATP1B3-007
 
ATP1B3-008
 
ATP1B3-010
 
ATP1B3-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ATP1B3-001 ENSP00000286371
ENST00000286371
P54709
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Show » Show » 279 31.5 No 1
ATP1B3-002 ENSP00000418280
ENST00000465172
F8WBY4
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Show » 44 5 No 0
ATP1B3-003 ENSP00000418952
ENST00000466678
Show » 43 4.8 No 0
ATP1B3-004 ENSP00000417522
ENST00000475483
C9JA36
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Show » 133 15 No 0
ATP1B3-007 ENSP00000418353
ENST00000462082
C9J6S2
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Show » 89 10 No 0
ATP1B3-008 ENSP00000419962
ENST00000495216
C9JXZ1
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Show » Show » 119 13.5 No 1
ATP1B3-010 ENSP00000417608
ENST00000487199
H7C4L9
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27 2.8 No 0
ATP1B3-201 ENSP00000440307
ENST00000539728
B7Z1N7
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Show » Show » 193 21.7 No 1