NCK2

GENE INFORMATION

? »

Gene name

NCK2 (HGNC Symbol)

Synonyms

NCKbeta

Description

NCK adaptor protein 2 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the NCK family of adaptor proteins. The protein contains three SH3 domains and one SH2 domain. The protein has no known catalytic function but has been shown to bind and recruit various proteins involved in the regulation of receptor protein tyrosine kinases. It is through these regulatory activities that this protein is believed to be involved in cytoskeletal reorganization. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]

Chromosome

2 (Chromosome progress)

Cytoband

q12.2

Chromosome location (bp)

106361354 - 106510730

Ensembl

ENSG00000071051 (version 73.37)

Entrez gene

8440

UniProt

O43639 (UniProt - Evidence at protein level)

neXtProt

NX_O43639

Antibodypedia

NCK2 antibodies
 

PROTEIN VIEW

? »
 
 
 
NCK2-001
 
NCK2-002
 
NCK2-003
 
NCK2-004
 
NCK2-005
 
NCK2-201
 
 
 
 
 

PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

NCK2-001 ENSP00000233154
ENST00000233154
O43639
Show all »
Show » Show » 380 42.9 No 0
NCK2-002 ENSP00000377018
ENST00000393349
O43639
Show all »
Show » Show » 380 42.9 No 0
NCK2-003 ENSP00000408040
ENST00000425756
E9PEE2
Show all »
Show » Show » 110 12.6 No 0
NCK2-004 ENSP00000377017
ENST00000393348
E7EPF5
Show all »
Show » Show » 144 16.4 No 0
NCK2-005 ENSP00000431109
ENST00000522586
E7ERP6
Show all »
Show » Show » 83 9.8 No 0
NCK2-201 ENSP00000410428
ENST00000451463
E7ERP6
Show all »
Show » Show » 83 9.8 No 0