ATP6AP1

GENE INFORMATION

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Gene name

ATP6AP1 (HGNC Symbol)

Synonyms

16A, Ac45, ATP6IP1, ATP6S1, CF2, ORF, VATPS1, XAP-3, XAP3

Description

ATPase, H+ transporting, lysosomal accessory protein 1 (HGNC Symbol)

Entrez gene summary

This gene encodes a component of a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. Vacuolar ATPase (V-ATPase) is comprised of a cytosolic V1 (site of the ATP catalytic site) and a transmembrane V0 domain. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, and receptor-mediated endocytosis. The encoded protein of this gene may assist in the V-ATPase-mediated acidification of neuroendocrine secretory granules. This protein may also play a role in early development. [provided by RefSeq, Aug 2013]

Chromosome

X (Chromosome progress)

Cytoband

q28

Chromosome location (bp)

153656978 - 153664862

Ensembl

ENSG00000071553 (version 73.37)

Entrez gene

537

UniProt

Q15904 (UniProt - Evidence at protein level)

neXtProt

NX_Q15904

Antibodypedia

ATP6AP1 antibodies
 

PROTEIN VIEW

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ATP6AP1-001
 
ATP6AP1-002
 
ATP6AP1-003
 
ATP6AP1-006
 
ATP6AP1-007
 
ATP6AP1-008
 
ATP6AP1-010
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ATP6AP1-001 ENSP00000358777
ENST00000369762
Q15904
Show all »
Show » Show » 470 52 Yes 1
ATP6AP1-002 ENSP00000396643
ENST00000455205
Show » 133 14.2 Yes 0
ATP6AP1-003 ENSP00000398511
ENST00000422890
A6NLC6
Show all »
Show » Show » 273 30.1 Yes 0
ATP6AP1-006 ENSP00000408470
ENST00000429585
H7C2Y8
Show all »
Show » Show » 128 13.9 Yes 0
ATP6AP1-007 ENSP00000408317
ENST00000439372
F2Z3L8
Show all »
Show » Show » 134 14.4 Yes 0
ATP6AP1-008 ENSP00000411209
ENST00000446552
F2Z3L8
Show all »
Show » Show » 134 14.4 Yes 0
ATP6AP1-010 ENSP00000392375
ENST00000449556
A6QRJ1
Show all »
Show » Show » 230 24.9 Yes 0