AFF4

GENE INFORMATION

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Gene name

AFF4 (HGNC Symbol)

Synonyms

AF5Q31, MCEF

Description

AF4/FMR2 family, member 4 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene belongs to the AF4 family of transcription factors involved in leukemia. It is a component of the positive transcription elongation factor b (P-TEFb) complex. A chromosomal translocation involving this gene and MLL gene on chromosome 11 is found in infant acute lymphoblastic leukemia with ins(5;11)(q31;q31q23). [provided by RefSeq, Oct 2011]

Chromosome

5 (Chromosome progress)

Cytoband

q31.1

Chromosome location (bp)

132211071 - 132299326

Ensembl

ENSG00000072364 (version 73.37)

Entrez gene

27125

UniProt

Q9UHB7 (UniProt - Evidence at protein level)

neXtProt

NX_Q9UHB7

Antibodypedia

AFF4 antibodies
 

PROTEIN VIEW

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AFF4-001
 
AFF4-004
 
AFF4-005
 
AFF4-009
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

AFF4-001 ENSP00000265343
ENST00000265343
Q9UHB7
Show all »
Show » Show » 1163 127.5 No 0
AFF4-004 ENSP00000367858
ENST00000378595
Q9UHB7
Show all »
Show » Show » 900 98.2 No 0
AFF4-005 ENSP00000409069
ENST00000425658
Show » 171 18 No 0
AFF4-009 ENSP00000395268
ENST00000421773
C9JCE0
Show all »
Show » Show » 148 16.3 No 0