P4HA2

GENE INFORMATION

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Gene name

P4HA2 (HGNC Symbol)

Synonyms

C-P4Halpha(II)

Description

prolyl 4-hydroxylase, alpha polypeptide II (HGNC Symbol)

Entrez gene summary

This gene encodes a component of prolyl 4-hydroxylase, a key enzyme in collagen synthesis composed of two identical alpha subunits and two beta subunits. The encoded protein is one of several different types of alpha subunits and provides the major part of the catalytic site of the active enzyme. In collagen and related proteins, prolyl 4-hydroxylase catalyzes the formation of 4-hydroxyproline that is essential to the proper three-dimensional folding of newly synthesized procollagen chains. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]

Chromosome

5 (Chromosome progress)

Cytoband

q31.1

Chromosome location (bp)

131527531 - 131631008

Ensembl

ENSG00000072682 (version 73.37)

Entrez gene

8974

UniProt

O15460 (UniProt - Evidence at protein level)

neXtProt

NX_O15460

Antibodypedia

P4HA2 antibodies
 

PROTEIN VIEW

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 « 
 
P4HA2-001
 
P4HA2-002
 
P4HA2-003
 
P4HA2-004
 
P4HA2-005
 
P4HA2-009
 
P4HA2-010
 
P4HA2-011
 
P4HA2-014
 
P4HA2-015
 
P4HA2-016
 
P4HA2-017
 
P4HA2-018
 
P4HA2-201
 
P4HA2-202
 
 » 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

P4HA2-001 ENSP00000384999
ENST00000401867
O15460
Show all »
Show » Show » 535 60.9 Yes 0
P4HA2-002 ENSP00000353772
ENST00000360568
O15460
Show all »
Show » Show » 533 60.6 Yes 0
P4HA2-003 ENSP00000166534
ENST00000166534
O15460
Show all »
Show » Show » 535 60.9 Yes 0
P4HA2-004 ENSP00000368379
ENST00000379086
O15460
Show all »
Show » Show » 533 60.6 Yes 0
P4HA2-005 ENSP00000413542
ENST00000453286
C9JX45
Show all »
Show » Show » 153 17.1 Yes 0
P4HA2-009 ENSP00000396495
ENST00000428369
C9JCP0
Show all »
Show » Show » 147 16.5 Yes 0
P4HA2-010 ENSP00000389523
ENST00000417528
E7ENX0
Show all »
Show » Show » 204 22.9 Yes 0
P4HA2-011 ENSP00000394953
ENST00000416053
C9JN43
Show all »
Show » Show » 101 11.4 Yes 0
P4HA2-014 ENSP00000391257
ENST00000431054
E7EPI9
Show all »
Show » Show » 236 26.6 Yes 0
P4HA2-015 ENSP00000405406
ENST00000439698
E7ERI1
Show all »
Show » Show » 184 20.6 Yes 0
P4HA2-016 ENSP00000403883
ENST00000418055
C9JIG4
Show all »
Show » Show » 114 12.7 Yes 0
P4HA2-017 ENSP00000378593
ENST00000395164
A8MXE0
Show all »
Show » Show » 167 18.7 Yes 0
P4HA2-018 ENSP00000395956
ENST00000428841
C9JFJ1
Show all »
Show » Show » 50 5.8 Yes 0
P4HA2-201 ENSP00000368394
ENST00000379100
O15460
Show all »
Show » Show » 533 60.6 Yes 0
P4HA2-202 ENSP00000368398
ENST00000379104
O15460
Show all »
Show » Show » 535 60.9 Yes 0