STK10

GENE INFORMATION

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Gene name

STK10 (HGNC Symbol)

Synonyms

LOK, PRO2729

Description

serine/threonine kinase 10 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the Ste20 family of serine/threonine protein kinases, and is similar to several known polo-like kinase kinases. The protein can associate with and phosphorylate polo-like kinase 1, and overexpression of a kinase-dead version of the protein interferes with normal cell cycle progression. The kinase can also negatively regulate interleukin 2 expression in T-cells via the mitogen activated protein kinase kinase 1 pathway. [provided by RefSeq, Jul 2008]

Chromosome

5 (Chromosome progress)

Cytoband

q35.1

Chromosome location (bp)

171469077 - 171615390

Ensembl

ENSG00000072786 (version 73.37)

Entrez gene

6793

UniProt

O94804 (UniProt - Evidence at protein level)

neXtProt

NX_O94804

Antibodypedia

STK10 antibodies
 

PROTEIN VIEW

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STK10-001
 
STK10-017
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

STK10-001 ENSP00000176763
ENST00000176763
O94804
Show all »
Show » Show » 968 112.1 No 0
STK10-017 ENSP00000428806
ENST00000520476
Show » 281 32.9 No 0