IKBKG

GENE INFORMATION

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Gene name

IKBKG (HGNC Symbol)

Synonyms

FIP-3, FIP3, Fip3p, IKK-gamma, IP1, IP2, NEMO, ZC2HC9

Description

inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma (HGNC Symbol)

Entrez gene summary

This gene encodes the regulatory subunit of the inhibitor of kappaB kinase (IKK) complex, which activates NF-kappaB resulting in activation of genes involved in inflammation, immunity, cell survival, and other pathways. Mutations in this gene result in incontinentia pigmenti, hypohidrotic ectodermal dysplasia, and several other types of immunodeficiencies. Multiple transcript variants encoding different isoforms have been found for this gene. A pseudogene highly similar to this locus is located in an adjacent region of the X chromosome. [provided by RefSeq, Aug 2011]

Chromosome

X (Chromosome progress)

Cytoband

q28

Chromosome location (bp)

153769414 - 153796782

Ensembl

ENSG00000073009 (version 73.37)

Entrez gene

8517

UniProt

Q9Y6K9 (UniProt - Evidence at protein level)

neXtProt

NX_Q9Y6K9

Antibodypedia

IKBKG antibodies
 

PROTEIN VIEW

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IKBKG-002
 
IKBKG-003
 
IKBKG-004
 
IKBKG-005
 
IKBKG-006
 
IKBKG-007
 
IKBKG-008
 
IKBKG-009
 
IKBKG-011
 
IKBKG-012
 
IKBKG-013
 
IKBKG-014
 
IKBKG-016
 
IKBKG-017
 
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PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

IKBKG-002 ENSP00000358622
ENST00000369609
Q9Y6K9
Show all »
Show » 487 55.8 No 0
IKBKG-003 ENSP00000358620
ENST00000369607
Q9Y6K9
Show all »
Show » 419 48.2 No 0
IKBKG-004 ENSP00000358619
ENST00000369606
Q9Y6K9
Show all »
Show » 419 48.2 No 0
IKBKG-005 ENSP00000358614
ENST00000369601
Q9Y6K9
Show all »
Show » 419 48.2 No 0
IKBKG-006 ENSP00000358615
ENST00000369602
Q9Y6K9
Show all »
Show » 320 37 No 0
IKBKG-007 ENSP00000394934
ENST00000440286
C9JN51
Show all »
Show » 251 28.8 No 0
IKBKG-008 ENSP00000390368
ENST00000422680
C9JH59
Show all »
Show » 206 23.7 No 0
IKBKG-009 ENSP00000398579
ENST00000413620
C9J2V2
Show all »
Show » 195 22.3 No 0
IKBKG-011 ENSP00000263518
ENST00000263518
F8W9A9
Show all »
Show » 368 42.4 No 0
IKBKG-012 ENSP00000395205
ENST00000445622
C9JCG6
Show all »
Show » 138 16.1 No 0
IKBKG-013 ENSP00000401308
ENST00000424839
C9JZ85
Show all »
190 21.7 No 0
IKBKG-014 ENSP00000420565
ENST00000470142
E7EU78
Show all »
Show » 412 47.4 No 0
IKBKG-016 ENSP00000377180
ENST00000393549
A8MV29
Show all »
Show » 411 47.3 No 0
IKBKG-017 ENSP00000400769
ENST00000455588
C9J1R1
Show all »
Show » 418 48.1 No 0