SDHA

GENE INFORMATION

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Gene name

SDHA (HGNC Symbol)

Synonyms

FP, SDH2, SDHF

Description

succinate dehydrogenase complex, subunit A, flavoprotein (Fp) (HGNC Symbol)

Entrez gene summary

This gene encodes a major catalytic subunit of succinate-ubiquinone oxidoreductase, a complex of the mitochondrial respiratory chain. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. Mutations in this gene have been associated with a form of mitochondrial respiratory chain deficiency known as Leigh Syndrome. A pseudogene has been identified on chromosome 3q29. [provided by RefSeq, Jul 2008]

Chromosome

5 (Chromosome progress)

Cytoband

p15.33

Chromosome location (bp)

218356 - 256815

Ensembl

ENSG00000073578 (version 73.37)

Entrez gene

6389

UniProt

P31040 (UniProt - Evidence at protein level)

neXtProt

NX_P31040

Antibodypedia

SDHA antibodies
 

PROTEIN VIEW

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SDHA-001
 
SDHA-002
 
SDHA-004
 
SDHA-010
 
SDHA-017
 
SDHA-018
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SDHA-001 ENSP00000264932
ENST00000264932
P31040
Show all »
Show » Show » 664 72.7 No 0
SDHA-002 ENSP00000426514
ENST00000504309
D6RFM5
Show all »
Show » Show » 583 63.6 No 0
SDHA-004 ENSP00000427703
ENST00000510361
E9PBJ5
Show all »
Show » 616 67.3 No 0
SDHA-010 ENSP00000425077
ENST00000509632
D6REB7
Show all »
89 10.1 No 0
SDHA-017 ENSP00000422404
ENST00000515815
126 13.5 No 0
SDHA-018 ENSP00000421911
ENST00000509564
H0Y8S2
Show all »
Show » 101 11.1 No 0