ADAM11

GENE INFORMATION

? »

Gene name

ADAM11 (HGNC Symbol)

Synonyms

MDC

Description

ADAM metallopeptidase domain 11 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the ADAM (a disintegrin and metalloprotease) protein family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This gene represents a candidate tumor supressor gene for human breast cancer based on its location within a minimal region of chromosome 17q21 previously defined by tumor deletion mapping. [provided by RefSeq, Jul 2008]

Chromosome

17 (Chromosome progress)

Cytoband

q21.31

Chromosome location (bp)

42836399 - 42859214

Ensembl

ENSG00000073670 (version 73.37)

Entrez gene

4185

UniProt

O75078 (UniProt - Evidence at transcript level)

neXtProt

NX_O75078

Antibodypedia

ADAM11 antibodies
 

PROTEIN VIEW

? »
 
 
 
ADAM11-001
 
ADAM11-002
 
ADAM11-004
 
ADAM11-005
 
 
 
 
 

PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ADAM11-001 ENSP00000200557
ENST00000200557
O75078
Show all »
Show » Show » 769 83.4 Yes 1
ADAM11-002 ENSP00000347856
ENST00000355638
H7BY08
Show all »
Show » 241 26.1 Yes 0
ADAM11-004 ENSP00000443773
ENST00000535346
B4DKD2
Show all »
Show » Show » 569 61.6 No 1
ADAM11-005 ENSP00000465537
ENST00000587773
K7EKA8
Show all »
Show » 517 57 No 0