SNCB

GENE INFORMATION

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Gene name

SNCB

Synonyms

Description

synuclein, beta (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is highly homologous to alpha-synuclein. These proteins are abundantly expressed in the brain and putatively inhibit phospholipase D2 selectively. The encoded protein, which may play a role in neuronal plasticity, is abundant in neurofibrillary lesions of patients with Alzheimer disease. This protein has been shown to be highly expressed in the substantia nigra of the brain, a region of neuronal degeneration in patients with Parkinson disease; however, no direct relation to Parkinson disease has been established. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

Chromosome

5 (Chromosome progress)

Cytoband

q35.2

Chromosome location (bp)

176047085 - 176057530

Ensembl

ENSG00000074317 (version 73.37)

Entrez gene

6620

UniProt

Q16143 (UniProt - Evidence at protein level)

neXtProt

NX_Q16143

Antibodypedia

SNCB antibodies
 

PROTEIN VIEW

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SNCB-001
 
SNCB-002
 
SNCB-003
 
SNCB-005
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SNCB-001 ENSP00000308057
ENST00000310112
Q16143
Show all »
Show » 134 14.3 No 0
SNCB-002 ENSP00000377296
ENST00000393693
Q16143
Show all »
Show » 134 14.3 No 0
SNCB-003 ENSP00000422223
ENST00000506696
Q16143
Show all »
Show » 134 14.3 No 0
SNCB-005 ENSP00000424073
ENST00000510387
Q16143
Show all »
Show » 134 14.3 No 0