CA12

GENE INFORMATION

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Gene name

CA12 (HGNC Symbol)

Synonyms

HsT18816

Description

carbonic anhydrase XII (HGNC Symbol)

Entrez gene summary

Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. This gene product is a type I membrane protein that is highly expressed in normal tissues, such as kidney, colon and pancreas, and has been found to be overexpressed in 10% of clear cell renal carcinomas. Two transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]

Chromosome

15 (Chromosome progress)

Cytoband

q22.2

Chromosome location (bp)

63613577 - 63674360

Ensembl

ENSG00000074410 (version 73.37)

Entrez gene

771

UniProt

O43570 (UniProt - Evidence at protein level)

neXtProt

NX_O43570

Antibodypedia

CA12 antibodies
 

PROTEIN VIEW

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CA12-001
 
CA12-002
 
CA12-003
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CA12-001 ENSP00000178638
ENST00000178638
O43570
Show all »
Show » Show » 354 39.5 Yes 1
CA12-002 ENSP00000343088
ENST00000344366
O43570
Show all »
Show » Show » 343 38.4 Yes 1
CA12-003 ENSP00000403028
ENST00000422263
B3KUB4
Show all »
Show » Show » 283 31.9 Yes 1