NOX3

GENE INFORMATION

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Gene name

NOX3 (HGNC Symbol)

Synonyms

GP91-3

Description

NADPH oxidase 3 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the NOX family of NADPH oxidases. These enzymes have the capacity to generate superoxide and other reactive oxygen species (ROS) and transport electrons across the plasma membrane. The ROS generated by family members have been implicated in numerous biological functions including host defense, posttranlational processing of proteins, cellular signaling, regulation of gene expression, and cell differentiation. The protein encoded by this gene is expressed predominantly in the inner ear and is involved in the biogenesis of otoconia/otolith, which are crystalline structures of the inner ear involved in the perception of gravity.[provided by RefSeq, May 2009]

Chromosome

6 (Chromosome progress)

Cytoband

q25.3

Chromosome location (bp)

155716504 - 155777037

Ensembl

ENSG00000074771 (version 73.37)

Entrez gene

50508

UniProt

Q9HBY0 (UniProt - Evidence at protein level)

neXtProt

NX_Q9HBY0

Antibodypedia

NOX3 antibodies
 

PROTEIN VIEW

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NOX3-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

NOX3-001 ENSP00000159060
ENST00000159060
Q9HBY0
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