CELSR1

GENE INFORMATION

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Gene name

CELSR1 (HGNC Symbol)

Synonyms

CDHF9, FMI2, HFMI2, ME2

Description

cadherin, EGF LAG seven-pass G-type receptor 1 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a member of the flamingo subfamily, part of the cadherin superfamily. The flamingo subfamily consists of nonclassic-type cadherins; a subpopulation that does not interact with catenins. The flamingo cadherins are located at the plasma membrane and have nine cadherin domains, seven epidermal growth factor-like repeats and two laminin A G-type repeats in their ectodomain. They also have seven transmembrane domains, a characteristic unique to this subfamily. It is postulated that these proteins are receptors involved in contact-mediated communication, with cadherin domains acting as homophilic binding regions and the EGF-like domains involved in cell adhesion and receptor-ligand interactions. This particular member is a developmentally regulated, neural-specific gene which plays an unspecified role in early embryogenesis. [provided by RefSeq, Jul 2008]

Chromosome

22 (Chromosome progress)

Cytoband

q13.31

Chromosome location (bp)

46756731 - 46933067

Ensembl

ENSG00000075275 (version 73.37)

Entrez gene

9620

UniProt

Q9NYQ6 (UniProt - Evidence at protein level)

neXtProt

NX_Q9NYQ6

Antibodypedia

CELSR1 antibodies
 

PROTEIN VIEW

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CELSR1-001
 
CELSR1-002
 
CELSR1-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CELSR1-001 ENSP00000262738
ENST00000262738
Q9NYQ6
Show all »
Show » Show » 3014 329.5 Yes 7
CELSR1-002 ENSP00000414689
ENST00000454637
Show » 772 85.4 No 0
CELSR1-201 ENSP00000379293
ENST00000395964
C9JDM9
Show all »
Show » Show » 1397 152.3 Yes 0