The primary data page shows the detailed antibody staining in 76 different cell types for each analyzed antibody. In addition, for each cell type, a knowledge-based annotated protein expression score based on all analyzed antibodies is displayed furthest to the right. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
The tissues and cell types can be ordered by organ, cell type or alphabetically. If ordered by organ, the tissues are presented in groups according to functional features. If ordered by cell type, the cells are presented in groups related to origin.
This score describes the level of antibody staining observed in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is based on the staining intensity and fraction of stained cells. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
This score describes a knowledge-based best estimate of the protein expression in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is a result of stringent evaluation of immunohistochemical staining pattern, RNA data from internal and external sources and available protein/gene characterization data. More information can be found in Assays & Annotation.
Summarizing texts describe the staining pattern for each antibody based on staining intensity, fraction of stained cells and subcellular localization. More information can be found in Assays & Annotation.
A majority of normal tissues displayed cytoplasmic and membranous staining. Strongest staining was observed placental trophoblasts, in plasma and in extracellular material.
Extracellular matrix in skin, uterus and cervix displayed positivity. Bile canaliculi and placenta showed moderate cytoplasmic positivity. Remaining normal cells were negative.
Extracellular matrix, smooth muscle, syncytiotrophoblasts in placenta and most female genitalia showed strong cytoplasmic staining.
Extracellular matrix was distinctly stained. Strong cytoplasmic positivity was observed in placental trophoblastic cells and subset of alveolar macrophages. Subset of cells in stomach and glandular cells of cervix were moderately stained. Glandular cells of uterus and parathyroid displayed moderate cytoplasmic and membranous staining. Remaining normal cell types were weakly stained or mostly negative.