FAP

GENE INFORMATION

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Gene name

FAP (HGNC Symbol)

Synonyms

DPPIV

Description

fibroblast activation protein, alpha (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a homodimeric integral membrane gelatinase belonging to the serine protease family. It is selectively expressed in reactive stromal fibroblasts of epithelial cancers, granulation tissue of healing wounds, and malignant cells of bone and soft tissue sarcomas. This protein is thought to be involved in the control of fibroblast growth or epithelial-mesenchymal interactions during development, tissue repair, and epithelial carcinogenesis. [provided by RefSeq, Jul 2008]

Chromosome

2 (Chromosome progress)

Cytoband

q24.2

Chromosome location (bp)

163027194 - 163101661

Ensembl

ENSG00000078098 (version 73.37)

Entrez gene

2191

UniProt

Q12884 (UniProt - Evidence at protein level)

neXtProt

NX_Q12884

Antibodypedia

FAP antibodies
 

PROTEIN VIEW

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FAP-001
 
FAP-004
 
FAP-007
 
FAP-012
 
FAP-014
 
FAP-015
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

FAP-001 ENSP00000188790
ENST00000188790
Q12884
Show all »
Show » Show » 760 87.7 Yes 0
FAP-004 ENSP00000417028
ENST00000422436
H7C4D9
Show all »
25 3 No 0
FAP-007 ENSP00000400137
ENST00000447386
C9J131
Show all »
Show » 155 18.2 No 0
FAP-012 ENSP00000407404
ENST00000450031
F8WF29
Show all »
Show » 121 14.2 No 0
FAP-014 ENSP00000441940
ENST00000462608
Show » 47 5.4 No 0
FAP-015 ENSP00000411391
ENST00000443424
B4DLR2
Show all »
Show » Show » 735 84.9 Yes 0