N4BP2

GENE INFORMATION

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Gene name

N4BP2 (HGNC Symbol)

Synonyms

B3BP

Description

NEDD4 binding protein 2 (HGNC Symbol)

Entrez gene summary

This gene encodes a protein containing a polynucleotide kinase domain (PNK) near the N-terminal region, and a Small MutS Related (Smr) domain near the C-terminal region. The encoded protein can bind to both B-cell leukemia/lymphoma 3 (BCL-3) and neural precursor cell expressed, developmentally downregulated 4, (Nedd4) proteins. This protein binds and hydrolyzes ATP, may function as a 5'-polynucleotide kinase, and has the capacity to be a ubiquitylation substrate. This protein may play a role in transcription-coupled DNA repair or genetic recombination. [provided by RefSeq, Jul 2008]

Chromosome

4 (Chromosome progress)

Cytoband

p14

Chromosome location (bp)

40058446 - 40159872

Ensembl

ENSG00000078177 (version 73.37)

Entrez gene

55728

UniProt

Q86UW6 (UniProt - Evidence at protein level)

neXtProt

NX_Q86UW6

Antibodypedia

N4BP2 antibodies
 

PROTEIN VIEW

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N4BP2-001
 
N4BP2-002
 
N4BP2-003
 
N4BP2-004
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

N4BP2-001 ENSP00000261435
ENST00000261435
Q86UW6
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Show » 1770 198.8 No 0
N4BP2-002 ENSP00000422436
ENST00000511480
D6RC09
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99 11 No 0
N4BP2-003 ENSP00000426430
ENST00000513269
1400 158.1 No 0
N4BP2-004 ENSP00000422057
ENST00000515550
D6R9J2
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Show » 173 19 No 0