DNM2

GENE INFORMATION

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Gene name

DNM2 (HGNC Symbol)

Synonyms

CMTDI1, CMTDIB, DI-CMTB, DYN2, DYNII

Description

dynamin 2 (HGNC Symbol)

Entrez gene summary

Dynamins represent one of the subfamilies of GTP-binding proteins. These proteins share considerable sequence similarity over the N-terminal portion of the molecule, which contains the GTPase domain. Dynamins are associated with microtubules. They have been implicated in cell processes such as endocytosis and cell motility, and in alterations of the membrane that accompany certain activities such as bone resorption by osteoclasts. Dynamins bind many proteins that bind actin and other cytoskeletal proteins. Dynamins can also self-assemble, a process that stimulates GTPase activity. Five alternatively spliced transcripts encoding different proteins have been described. Additional alternatively spliced transcripts may exist, but their full-length nature has not been determined. [provided by RefSeq, Jun 2010]

Chromosome

19 (Chromosome progress)

Cytoband

p13.2

Chromosome location (bp)

10828755 - 10944164

Ensembl

ENSG00000079805 (version 73.37)

Entrez gene

1785

UniProt

P50570 (UniProt - Evidence at protein level)

neXtProt

NX_P50570

Antibodypedia

DNM2 antibodies
 

PROTEIN VIEW

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DNM2-001
 
DNM2-002
 
DNM2-003
 
DNM2-006
 
DNM2-010
 
DNM2-012
 
DNM2-022
 
DNM2-023
 
DNM2-024
 
DNM2-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

DNM2-001 ENSP00000347890
ENST00000355667
P50570
Show all »
Show » Show » 870 98.1 No 0
DNM2-002 ENSP00000352721
ENST00000359692
P50570
Show all »
Show » Show » 866 97.7 No 0
DNM2-003 ENSP00000386192
ENST00000408974
P50570
Show all »
Show » Show » 866 97.6 No 0
DNM2-006 ENSP00000468734
ENST00000585892
K7ESI9
Show all »
Show » 869 98 No 0
DNM2-010 ENSP00000373905
ENST00000389253
P50570
Show all »
Show » Show » 870 98 No 0
DNM2-012 ENSP00000467430
ENST00000586939
K7EPK9
Show all »
Show » 51 5.5 No 0
DNM2-022 ENSP00000466603
ENST00000587830
Show » 289 33.7 No 0
DNM2-023 ENSP00000466914
ENST00000589106
137 14.3 No 0
DNM2-024 ENSP00000466621
ENST00000591818
K7EMR9
Show all »
169 18.2 No 0
DNM2-201 ENSP00000313164
ENST00000314646
F5H4R9
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Show » 870 98 No 0