SRCAP

GENE INFORMATION

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Gene name

SRCAP (HGNC Symbol)

Synonyms

DOMO1, EAF1, KIAA0309, SWR1

Description

Snf2-related CREBBP activator protein (HGNC Symbol)

Entrez gene summary

This gene encodes the core catalytic component of the multiprotein chromatin-remodeling SRCAP complex. The encoded protein is an ATPase that is necessary for the incorporation of the histone variant H2A.Z into nucleosomes. It can function as a transcriptional activator in Notch-mediated, CREB-mediated and steroid receptor-mediated transcription. Mutations in this gene cause Floating-Harbor syndrome, a rare disorder characterized by short stature, language deficits and dysmorphic facial features. [provided by RefSeq, Feb 2012]

Chromosome

16 (Chromosome progress)

Cytoband

p11.2

Chromosome location (bp)

30709530 - 30755602

Ensembl

ENSG00000080603 (version 73.37)

Entrez gene

10847

UniProt

Q6ZRS2 (UniProt - Evidence at protein level)

neXtProt

NX_Q6ZRS2

Antibodypedia

SRCAP antibodies
 

PROTEIN VIEW

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SRCAP-001
 
SRCAP-002
 
SRCAP-004
 
SRCAP-201
 
SRCAP-202
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SRCAP-001 ENSP00000262518
ENST00000262518
Q6ZRS2
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Show » Show » 3230 343.6 No 0
SRCAP-002 ENSP00000369719
ENST00000380361
Q6ZRS2
Show all »
Show » Show » 3053 325.8 No 0
SRCAP-004 ENSP00000405186
ENST00000411466
C9J4U4
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100 10 No 0
SRCAP-201 ENSP00000343042
ENST00000344771
Q6ZRS2
Show all »
Show » Show » 3072 327.8 No 0
SRCAP-202 ENSP00000378499
ENST00000395059
Q6ZRS2
Show all »
Show » Show » 3168 337.4 No 0