CPOX

GENE INFORMATION

? »

Gene name

CPOX (HGNC Symbol)

Synonyms

CPO, CPX, HCP

Description

coproporphyrinogen oxidase (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is the sixth enzyme of the heme biosynthetic pathway. The encoded enzyme is soluble and found in the intermembrane space of mitochondria. This enzyme catalyzes the stepwise oxidative decarboxylation of coproporphyrinogen III to protoporphyrinogen IX, a precursor of heme. Defects in this gene are a cause of hereditary coproporphyria (HCP).[provided by RefSeq, Oct 2009]

Chromosome

3 (Chromosome progress)

Cytoband

q11.2

Chromosome location (bp)

98239976 - 98312567

Ensembl

ENSG00000080819 (version 73.37)

Entrez gene

1371

UniProt

P36551 (UniProt - Evidence at protein level)

neXtProt

NX_P36551

Antibodypedia

CPOX antibodies
 

PROTEIN VIEW

? »
 
 
 
CPOX-001
 
CPOX-003
 
CPOX-005
 
 
 
 
 

PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CPOX-001 ENSP00000264193
ENST00000264193
P36551
Show all »
Show » Show » 454 50.2 No 1
CPOX-003 ENSP00000424924
ENST00000513674
D6RER6
Show all »
Show » Show » 175 18.3 No 1
CPOX-005 ENSP00000425880
ENST00000512905
Show » 70 8.1 No 0