PGR

GENE INFORMATION

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Gene name

PGR (HGNC Symbol)

Synonyms

NR3C3, PR

Description

progesterone receptor (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy. This gene uses two distinct promotors and translation start sites in the first exon to produce two isoforms, A and B. The two isoforms are identical except for the additional 165 amino acids found in the N-terminus of isoform B and mediate their own response genes and physiologic effects with little overlap. [provided by RefSeq, Jan 2011]

Chromosome

11 (Chromosome progress)

Cytoband

q22.1

Chromosome location (bp)

100900355 - 101001255

Ensembl

ENSG00000082175 (version 73.37)

Entrez gene

5241

UniProt

P06401 (UniProt - Evidence at protein level)

neXtProt

NX_P06401

Antibodypedia

PGR antibodies
 

PROTEIN VIEW

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PGR-001
 
PGR-002
 
PGR-004
 
PGR-005
 
PGR-006
 
PGR-007
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PGR-001 ENSP00000325120
ENST00000325455
P06401
Show all »
Show » Show » 933 99 No 0
PGR-002 ENSP00000436561
ENST00000534013
P06401
Show all »
Show » Show » 339 38.8 No 0
PGR-004 ENSP00000432914
ENST00000528960
Q8NG44
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Show » Show » 764 79.3 No 0
PGR-005 ENSP00000432352
ENST00000534780
Q8NG42
Show all »
Show » Show » 803 83.7 No 0
PGR-006 ENSP00000263463
ENST00000263463
Q8TDS3
Show all »
Show » Show » 831 87.7 No 0
PGR-007 ENSP00000436803
ENST00000526300
Q8NG45
Show all »
Show » Show » 695 71.7 No 0