Fields »

SUBCELLULAR LOCATION

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Main location(s)

Mitochondria

Additional location(s)

Vesicles 

Staining summary

Mainly localized to mitochondria but also to vesicles.

Reliability (APE)

High

Antibodies in assay

HPA008247, HPA008880
 

Antibody HPA008247

 

Antibody HPA008880

 

         Cell line A-431

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Location(s)

Mitochondria Mitochondria, Vesicles 

Staining characteristics

  

Staining intensity

Strong Weak 

Validation

One/multiple location(s) supported by experimental gene/protein characterization data.
 
Multiple locations partly supported (at least one) by experimental gene/protein characterization data.
 

Comment

  

         Cell line U-2 OS

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Location(s)

Mitochondria Mitochondria, Vesicles 

Staining characteristics

  

Staining intensity

Moderate Weak 

Validation

One/multiple location(s) supported by experimental gene/protein characterization data.
 
Multiple locations partly supported (at least one) by experimental gene/protein characterization data.
 

Comment

  

         Cell line U-251 MG

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Location(s)

Mitochondria Vesicles 

Staining characteristics

  

Staining intensity

Weak Weak 

Validation

One/multiple location(s) supported by experimental gene/protein characterization data.
 
Location not consistent with experimental gene/protein characterization data.
 

Comment

  

         Antibody summary


Immunofluorescent staining of human cell line U-2 OS shows positivity in mitochondria.
 

Immunofluorescent staining of human cell line U-2 OS shows positivity in mitochondria & vesicles.
 

Summary

Staining of mitochondria in all three cell lines.   Staining of vesicles in all three cell lines with additional staining of mitochondria in A-431 and U-2 OS.  

Validation

The subcellular location is supported by literature.
 
The subcellular location is supported by literature.
 

Dictionary

Mitochondria
Endosome