KCNK2

GENE INFORMATION

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Gene name

KCNK2 (HGNC Symbol)

Synonyms

K2p2.1, TREK-1

Description

potassium channel, subfamily K, member 2 (HGNC Symbol)

Entrez gene summary

This gene encodes one of the members of the two-pore-domain background potassium channel protein family. This type of potassium channel is formed by two homodimers that create a channel that leaks potassium out of the cell to control resting membrane potential. The channel can be opened, however, by certain anesthetics, membrane stretching, intracellular acidosis, and heat. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Chromosome

1 (Chromosome progress)

Cytoband

q41

Chromosome location (bp)

215179118 - 215410436

Ensembl

ENSG00000082482 (version 73.37)

Entrez gene

3776

UniProt

O95069 (UniProt - Evidence at transcript level)

neXtProt

NX_O95069

Antibodypedia

KCNK2 antibodies
 

PROTEIN VIEW

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KCNK2-001
 
KCNK2-002
 
KCNK2-003
 
KCNK2-005
 
KCNK2-007
 
KCNK2-008
 
KCNK2-009
 
KCNK2-010
 
KCNK2-011
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

KCNK2-001 ENSP00000394033
ENST00000444842
O95069
Show all »
Show » Show » 426 47.1 No 6
KCNK2-002 ENSP00000375764
ENST00000391894
O95069
Show all »
Show » Show » 411 45.5 No 6
KCNK2-003 ENSP00000413460
ENST00000457122
C9JXY2
Show all »
Show » Show » 125 13.7 No 2
KCNK2-005 ENSP00000420203
ENST00000467031
Q5DP47
Show all »
Show » Show » 228 24.7 No 3
KCNK2-007 ENSP00000418706
ENST00000486921
Q6ZW95
Show all »
Show » Show » 152 17.2 No 1
KCNK2-008 ENSP00000375765
ENST00000391895
O95069
Show all »
Show » Show » 422 46.9 No 6
KCNK2-009 ENSP00000419633
ENST00000470177
B4DGU6
Show all »
Show » Show » 156 17.5 No 1
KCNK2-010 ENSP00000420499
ENST00000474771
F8WDE6
Show all »
Show » Show » 217 23.3 No 3
KCNK2-011 ENSP00000420569
ENST00000478774
C9JDK1
Show all »
Show » Show » 118 12.9 No 2