OPRK1

GENERAL INFORMATION

? »

Gene name

OPRK1

Gene description

Opioid receptor, kappa 1

Protein class

FDA approved drug targets
G-protein coupled receptors
Predicted membrane proteins

Predicted localization

Membrane

Number of transcripts

5
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

? »

RNA tissue category

HPA:Tissue enhanced (cerebral cortex, prostate)
GTEx:Tissue enhanced (cerebellum, cerebral cortex)

Protein evidence

Evidence at protein level

Protein localization

Cytoplasmic expression in CNS and prostate.

ANTIBODY RELIABILITY

? »

Data reliability
description

Antibody staining not consistent with RNA expression data. Presumed off target binding observed and disregarded.

Data reliability

Uncertain based on 1 antibody.
CAB022595
SHOW MORE

RNA AND PROTEIN EXPRESSION SUMMARY

? »
RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

? »

Organ

Expression



RNA EXPRESSION OVERVIEW

? »
HPA dataset
RNA tissue category:  Tissue enhanced (cerebral cortex, prostate)

Organ

Expression

GTEx dataset
RNA tissue category:  Tissue enhanced (cerebellum, cerebral cortex)

Organ

Expression



GENE INFORMATION

? »

Gene name

OPRK1 (HGNC Symbol)

Synonyms

KOR, OPRK

Description

Opioid receptor, kappa 1 (HGNC Symbol)

Entrez gene summary

Chromosome

8

Cytoband

q11.23

Chromosome location (bp)

53225716 - 53251697

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000082556 (version 78.38)

Entrez gene

4986

UniProt

P41145 (UniProt - Evidence at protein level)

neXtProt

NX_P41145

Antibodypedia

OPRK1 antibodies


PROTEIN BROWSER

? »
 
 
 
ENST00000265572
 
ENST00000520287
 
ENST00000524278
 
ENST00000612786
 
ENST00000613482
 
 
 
 


PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

OPRK1-001 ENSP00000265572
ENST00000265572
P41145
Show all »
Show » Show » 380 42.6 No 7
OPRK1-004 ENSP00000429706
ENST00000520287
P41145
Show all »
Show » Show » 380 42.6 No 7
OPRK1-005 ENSP00000430923
ENST00000524278
P41145
Show all »
Show » Show » 291 33.3 No 6
OPRK1-201 ENSP00000483000
ENST00000612786
P41145
Show all »
Show » Show » 291 33.3 No 6
OPRK1-202 ENSP00000478453
ENST00000613482
Show » Show » 366 41.1 No 7