GSK3B

GENE INFORMATION

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Gene name

GSK3B

Synonyms

Description

glycogen synthase kinase 3 beta (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a serine-threonine kinase, belonging to the glycogen synthase kinase subfamily. It is involved in energy metabolism, neuronal cell development, and body pattern formation. Polymorphisms in this gene have been implicated in modifying risk of Parkinson disease, and studies in mice show that overexpression of this gene may be relevant to the pathogenesis of Alzheimer disease. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009]

Chromosome

3 (Chromosome progress)

Cytoband

q13.33

Chromosome location (bp)

119540170 - 119813264

Ensembl

ENSG00000082701 (version 73.37)

Entrez gene

2932

UniProt

P49841 (UniProt - Evidence at protein level)

neXtProt

NX_P49841

Antibodypedia

GSK3B antibodies
 

PROTEIN VIEW

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GSK3B-001
 
GSK3B-002
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

GSK3B-001 ENSP00000264235
ENST00000264235
P49841
Show all »
Show » Show » 420 46.7 No 0
GSK3B-002 ENSP00000324806
ENST00000316626
P49841
Show all »
Show » Show » 433 48 No 0