RRAGB

GENERAL INFORMATION

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Gene name

RRAGB

Gene description

Ras-related GTP binding B

Protein class

Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

3
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all

Protein evidence

Evidence at protein level

Protein localization

General cytoplasmic expression with a granular pattern.

ANTIBODY RELIABILITY

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Data reliability
description

Antibody staining mainly consistent with RNA expression data. Caution, targets protein from more than one gene. Pending external verification.

Data reliability

Uncertain based on 1 antibody.
HPA003734
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Expressed in all

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

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Gene name

RRAGB

Synonyms

Description

Ras-related GTP binding B (HGNC Symbol)

Entrez gene summary

Ras-homologous GTPases constitute a large family of signal transducers that alternate between an activated, GTP-binding state and an inactivated, GDP-binding state. These proteins represent cellular switches that are operated by GTP-exchange factors and factors that stimulate their intrinsic GTPase activity. All GTPases of the Ras superfamily have in common the presence of six conserved motifs involved in GTP/GDP binding, three of which are phosphate-/magnesium-binding sites (PM1-PM3) and three of which are guanine nucleotide-binding sites (G1-G3). Transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Jul 2008]

Chromosome

X

Cytoband

p11.21

Chromosome location (bp)

55717739 - 55758774

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000083750 (version 78.38)

Entrez gene

10325

UniProt

Q5VZM2 (UniProt - Evidence at protein level)

neXtProt

NX_Q5VZM2

Antibodypedia

RRAGB antibodies


PROTEIN BROWSER

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ENST00000262850
 
ENST00000374941
 
ENST00000414239
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

RRAGB-001 ENSP00000262850
ENST00000262850
Q5VZM2
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Show » Show » 374 43.3 No 0
RRAGB-002 ENSP00000364077
ENST00000374941
Q5VZM2
Show all »
Show » Show » 346 40.2 No 0
RRAGB-005 ENSP00000410630
ENST00000414239
Q5VZM0
Show all »
Show » Show » 194 22.9 No 0