PPIE

GENE INFORMATION

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Gene name

PPIE (HGNC Symbol)

Synonyms

CyP-33, MGC111222, MGC3736

Description

peptidylprolyl isomerase E (cyclophilin E) (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. This protein contains a highly conserved cyclophilin (CYP) domain as well as an RNA-binding domain. It was shown to possess PPIase and protein folding activities, and it also exhibits RNA-binding activity. Alternative splicing results in multiple transcript variants. A related pseudogene, which is also located on chromosome 1, has been identified. [provided by RefSeq, Aug 2010]

Chromosome

1 (Chromosome progress)

Cytoband

p34.2

Chromosome location (bp)

40157854 - 40229586

Ensembl

ENSG00000084072 (version 73.37)

Entrez gene

10450

UniProt

Q9UNP9 (UniProt - Evidence at protein level)

neXtProt

NX_Q9UNP9

Antibodypedia

PPIE antibodies
 

PROTEIN VIEW

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PPIE-001
 
PPIE-002
 
PPIE-003
 
PPIE-004
 
PPIE-006
 
PPIE-007
 
PPIE-008
 
PPIE-009
 
PPIE-011
 
PPIE-013
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PPIE-001 ENSP00000312769
ENST00000324379
Q9UNP9
Show all »
Show » Show » 301 33.4 No 0
PPIE-002 ENSP00000348904
ENST00000356511
Q9UNP9
Show all »
Show » Show » 296 33.1 No 0
PPIE-003 ENSP00000361918
ENST00000372830
Q9UNP9
Show all »
Show » Show » 314 35 No 0
PPIE-004 ENSP00000434989
ENST00000495526
E9PMH0
Show all »
38 4.3 No 0
PPIE-006 ENSP00000433475
ENST00000497370
E9PKY5
Show all »
Show » 213 23.8 No 0
PPIE-007 ENSP00000361925
ENST00000372835
E9PEQ6
Show all »
Show » 250 27.7 No 0
PPIE-008 ENSP00000436689
ENST00000470018
E9PIB0
Show all »
72 8.2 No 0
PPIE-009 ENSP00000431714
ENST00000470213
E9PK21
Show all »
Show » 208 22.8 No 0
PPIE-011 ENSP00000432396
ENST00000474804
H0YCV4
Show all »
37 4.2 No 0
PPIE-013 ENSP00000434888
ENST00000475350
36 4 No 0