NCOA1

GENE INFORMATION

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Gene name

NCOA1 (HGNC Symbol)

Synonyms

bHLHe74, F-SRC-1, KAT13A, NCoA-1, RIP160, SRC1

Description

nuclear receptor coactivator 1 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene acts as a transcriptional coactivator for steroid and nuclear hormone receptors. It is a member of the p160/steroid receptor coactivator (SRC) family and like other family members has histone acetyltransferase activity and contains a nuclear localization signal, as well as bHLH and PAS domains. The product of this gene binds nuclear receptors directly and stimulates the transcriptional activities in a hormone-dependent fashion. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]

Chromosome

2 (Chromosome progress)

Cytoband

p23.3

Chromosome location (bp)

24714783 - 24993571

Ensembl

ENSG00000084676 (version 73.37)

Entrez gene

8648

UniProt

Q15788 (UniProt - Evidence at protein level)

neXtProt

NX_Q15788

Antibodypedia

NCOA1 antibodies
 

PROTEIN VIEW

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NCOA1-001
 
NCOA1-002
 
NCOA1-003
 
NCOA1-009
 
NCOA1-201
 
NCOA1-202
 
NCOA1-203
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

NCOA1-001 ENSP00000385216
ENST00000406961
Q15788
Show all »
Show » Show » 1441 156.8 No 0
NCOA1-002 ENSP00000385097
ENST00000405141
Q15788
Show all »
Show » Show » 1399 152.4 No 0
NCOA1-003 ENSP00000379197
ENST00000395856
Q15788
Show all »
Show » Show » 1440 156.6 No 0
NCOA1-009 ENSP00000385195
ENST00000407230
B5MCN7
Show all »
Show » Show » 1248 135.6 No 0
NCOA1-201 ENSP00000288599
ENST00000288599
Q15788
Show all »
Show » Show » 1399 152.4 No 0
NCOA1-202 ENSP00000320940
ENST00000348332
Q15788
Show all »
Show » Show » 1441 156.8 No 0
NCOA1-203 ENSP00000444039
ENST00000538539
Q15788
Show all »
Show » Show » 1399 152.4 No 0