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TISSUE MIDBRAIN Show tissue menu
ADIPOSE TISSUE ADRENAL GLAND AMYGDALA APPENDIX BASAL GANGLIA BONE MARROW BREAST CEREBELLUM CEREBRAL CORTEX CERVIX CHOROID PLEXUS COLON DUODENUM ENDOMETRIUM
EPIDIDYMIS ESOPHAGUS FALLOPIAN TUBE GALLBLADDER HEART MUSCLE HIPPOCAMPAL FORMATION HYPOTHALAMUS KIDNEY LIVER LUNG LYMPH NODE MEDULLA OBLONGATA MIDBRAIN OVARY
PANCREAS PARATHYROID GLAND PITUITARY GLAND PLACENTA PONS PROSTATE RECTUM RETINA SALIVARY GLAND SEMINAL VESICLE SKELETAL MUSCLE SKIN SMALL INTESTINE SMOOTH MUSCLE
SPINAL CORD SPLEEN STOMACH TESTIS THALAMUS THYMUS THYROID GLAND TONGUE TONSIL URINARY BLADDER VAGINA WHITE MATTER
Dictionary
Tissue proteome
Midbrain
MIDBRAIN - Expression summary
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

Read more
No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Read more
Consensus:10.9 nTPM
HPA:10.9 nTPM
GTEx:34.7 nTPM
FANTOM5:29.3 Scaled Tags Per Million
Pig:39.5 nTPM
Mouse:82.4 nTPM
Allen mouse:3.2 Expression energy

MIDBRAIN - Annotated protein expression
Pending normal tissue analysis

MIDBRAIN - HPA Brain RNA-seq
Max nTPM 10.9
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 2.1
2666 Male, age 74, left hemisphere 17.2
1827 Male, age 72, unknown 2.3
2219 Male, age 76, both hemispheres 1.2
2586 Male, age 75, left hemisphere 0.8
1830 Male, age 51, unknown 0.0
1833 Male, age 53, unknown 0.0
1870 Female, age 42, unknown 0.0
2019 Male, age 18, unknown 0.0
2411 Female, age 72, unknown 0.0
2828 Female, age 72, unknown 0.0
Dorsal raphe nucleus
nTPM: 0.0
1828 Male, age 53, unknown 0.0
2016 Female, age 72, unknown 0.0
2047 Male, age 72, unknown 0.0
2298 Female, age 72, unknown 0.0
2750 Male, age 76, both hemispheres 0.0
Inferior colliculus
nTPM: 0.0
1848 Female, age 42, unknown 0.0
1890 Male, age 53, unknown 0.0
2097 Female, age 72, unknown 0.0
2849 Male, age 72, unknown 0.0
Median raphe nucleus
nTPM: 0.3
2220 Male, age 76, midline 0.3
Pedunculopontine tegmental nucleus
nTPM: 0.0
1921 Female, age 85, both hemispheres 0.2
2334 Male, age 80, both hemispheres 0.0
2338 Male, age 61, both hemispheres 0.0
Periaquaductal grey, anterior
nTPM: 1.7
1795 Male, age 51, unknown 5.2
1947 Male, age 18, unknown 0.0
2502 Female, age 75, unknown 0.0
Periaquaductal grey, dorsal
nTPM: 0.0
1831 Male, age 72, unknown 0.0
1840 Male, age 53, unknown 0.0
2464 Female, age 72, unknown 0.0
2850 Male, age 76, both hemispheres 0.0
Periaquaductal grey, lateral
nTPM: 0.0
2053 Male, age 18, unknown 0.0
2140 Male, age 76, both hemispheres 0.0
2272 Male, age 74, both hemispheres 0.0
Pretectal area
nTPM: 4.8
1816 Male, age 51, unknown 21.5
1944 Female, age 72, unknown 18.7
2007 Male, age 72, unknown 6.8
1817 Female, age 42, unknown 6.6
1815 Male, age 53, unknown 0.0
2224 Female, age 72, unknown 0.0
2273 Male, age 74, both hemispheres 0.0
2316 Male, age 76, right hemisphere 0.0
2407 Male, age 75, both hemispheres 0.0
2667 Female, age 75, unknown 0.0
2825 Male, age 18, unknown 0.0
Red nucleus
nTPM: 0.0
1821 Female, age 72, unknown 0.0
1865 Male, age 51, unknown 0.0
1904 Male, age 53, unknown 0.0
1954 Female, age 42, unknown 0.0
2227 Male, age 72, unknown 0.0
2503 Female, age 72, unknown 0.0
2584 Male, age 75, left hemisphere 0.0
2588 Male, age 74, left hemisphere 0.0
2725 Female, age 75, unknown 0.0
2769 Male, age 72, unknown 0.0
2785 Male, age 18, unknown 0.0
2823 Male, age 76, right hemisphere 0.0
Substantia nigra
nTPM: 10.9
1916 Female, age 42, unknown 39.8
1941 Male, age 53, unknown 29.9
2665 Male, age 74, both hemispheres 17.2
1851 Male, age 51, unknown 14.1
1889 Female, age 72, unknown 6.0
2241 Male, age 72, unknown 2.0
2409 Female, age 72, unknown 0.0
2583 Male, age 75, right hemisphere 0.0
2590 Female, age 75, unknown 0.0
2699 Male, age 18, unknown 0.0
Superior colliculus
nTPM: 3.5
2668 Female, age 75, unknown 25.4
2087 Female, age 72, unknown 9.0
1796 Male, age 53, unknown 1.2
1839 Male, age 51, unknown 0.0
1895 Male, age 76, right hemisphere 0.0
1913 Female, age 42, unknown 0.0
1995 Male, age 72, unknown 0.0
2261 Male, age 18, unknown 0.0
2587 Male, age 74, left hemisphere 0.0
2664 Male, age 75, both hemispheres 0.0
Ventral tegmental area
nTPM: 4.6
2218 Male, age 76, both hemispheres 9.9
2410 Female, age 72, unknown 9.1
1915 Female, age 42, unknown 8.7
1942 Male, age 51, unknown 0.0
2021 Male, age 53, unknown 0.0
2223 Female, age 72, unknown 0.0

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 34.7
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 34.7
Samples: 139

Max nTPM: 158.0
Min nTPM: 7.2
Std nTPM: 26.9
Median nTPM: 25.1
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 158.0
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 134.7
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 123.2
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 113.8
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 105.4
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 100.7
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 93.3
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 85.8
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 79.7
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 76.8
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 74.1
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 73.7
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 72.4
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 70.3
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 69.0
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 68.5
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 65.0
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 63.7
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 63.5
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 62.7
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 60.3
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 57.3
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 56.3
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 56.2
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 56.0
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 55.0
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 54.5
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 53.3
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 52.2
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 52.0
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 50.5
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 50.0
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 47.6
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 45.0
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 43.9
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 43.1
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 43.0
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 42.2
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 40.7
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 38.9
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 38.4
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 38.1
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 37.5
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 36.6
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 36.2
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 36.1
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 35.3
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 35.2
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 35.0
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 35.0
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 34.5
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 33.2
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 33.0
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 32.6
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 32.5
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 32.4
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 31.8
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 31.3
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 31.0
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 30.8
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 30.6
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 29.7
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 29.2
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 29.2
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 28.6
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 28.5
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 27.8
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 26.2
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 25.2
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 25.1
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 24.4
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 23.8
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 23.3
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 22.7
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 22.5
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 22.4
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 22.3
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 22.1
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 21.7
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 21.4
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 21.3
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 21.3
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 21.1
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 20.2
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 20.2
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 20.1
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 19.8
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 19.7
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 19.6
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 19.2
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 18.8
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 18.7
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 18.4
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 18.3
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 18.2
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 18.2
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 17.3
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 17.2
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 17.2
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 17.2
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 16.9
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 16.9
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 16.8
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 16.8
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 16.2
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 15.7
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 15.5
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 15.4
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 14.6
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 14.5
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 14.3
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 14.1
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 14.0
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 13.9
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 13.8
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 13.7
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 13.7
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 13.4
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 13.4
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 12.7
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 12.6
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 12.5
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 12.4
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 12.3
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 12.3
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 12.3
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 12.0
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 11.6
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 11.5
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 11.3
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 11.2
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 10.8
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 10.6
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 10.4
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 9.7
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 9.3
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 8.2
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 7.5
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 7.2
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Read more
Max Scaled Tags Per Million 29.3
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 29.3
FF:10158-103A5 76 years, female 29.3

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 39.5
Pig sample Sample description nTPM
Midbrain
nTPM: 36.4
Samples: 4

Max nTPM: 63.3
Min nTPM: 11.8
Sample A Female 11.8
Sample B Female 27.6
Sample C Male 63.3
Sample D Male 43.0
Periaqueductal gray
nTPM: 27.6
Samples: 3

Max nTPM: 38.6
Min nTPM: 21.8
Sample B Female 22.5
Sample C Male 38.6
Sample D Male 21.8
Substantia nigra
nTPM: 39.5
Samples: 4

Max nTPM: 59.8
Min nTPM: 13.4
Sample A Female 59.8
Sample B Female 26.2
Sample C Male 58.6
Sample D Male 13.4
Superior colliculi
nTPM: 36.7
Samples: 4

Max nTPM: 51.9
Min nTPM: 17.4
Sample A Female 38.2
Sample B Female 17.4
Sample C Male 51.9
Sample D Male 39.3

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Read more
Average nTPM 82.4
Mouse sample Sample description nTPM
Midbrain
nTPM: 82.4
Samples: 4

Max nTPM: 85.4
Min nTPM: 74.4
Sample A Male 74.4
Sample B Male 84.6
Sample C Female 85.4
Sample D Female 85.2

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Read more
Max Expression energy 3.2
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 3.2
69735795 Antisense, RP_050503_03_E11, Mouse strain C57BL/6J (56 days, male) 6.2
70200848 Antisense, RP_050517_02_G02, Mouse strain C57BL/6J (56 days, male) 0.2

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