EIF2AK1

GENE INFORMATION

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Gene name

EIF2AK1 (HGNC Symbol)

Synonyms

HRI, KIAA1369

Description

Eukaryotic translation initiation factor 2-alpha kinase 1 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene acts at the level of translation initiation to downregulate protein synthesis in response to stress. The encoded protein is a kinase that can be inactivated by hemin. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]

Chromosome

7

Cytoband

p22.1

Chromosome location (bp)

6061881 - 6098861

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000086232 (version 75.37)

Entrez gene

27102

UniProt

Q9BQI3 (UniProt - Evidence at protein level)

neXtProt

NX_Q9BQI3

Antibodypedia

EIF2AK1 antibodies
 

PROTEIN VIEW

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EIF2AK1-001
 
EIF2AK1-003
 
EIF2AK1-004
 
EIF2AK1-011
 
EIF2AK1-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

EIF2AK1-001 ENSP00000199389
ENST00000199389
Q9BQI3
Show all »
Show » Show » 630 71.1 No 0
EIF2AK1-003 ENSP00000392459
ENST00000431744
F8WCM0
Show all »
Show » 81 8.5 No 0
EIF2AK1-004 ENSP00000397590
ENST00000446699
C9J7U7
Show all »
Show » 164 18.5 No 0
EIF2AK1-011 ENSP00000392734
ENST00000422786
Show » 72 7.5 Yes 0
EIF2AK1-201 ENSP00000445784
ENST00000536084
B4DIP4
Show all »
Show » Show » 577 65.3 No 0