MRPL28

GENE INFORMATION

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Gene name

MRPL28 (HGNC Symbol)

Synonyms

MAAT1, p15

Description

mitochondrial ribosomal protein L28 (HGNC Symbol)

Entrez gene summary

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein, a part of which was originally isolated by its ability to recognize tyrosinase in an HLA-A24-restricted fashion. [provided by RefSeq, Jul 2008]

Chromosome

16 (Chromosome progress)

Cytoband

p13.3

Chromosome location (bp)

417384 - 420527

Ensembl

ENSG00000086504 (version 73.37)

Entrez gene

10573

UniProt

Q13084 (UniProt - Evidence at protein level)

neXtProt

NX_Q13084

Antibodypedia

MRPL28 antibodies
 

PROTEIN VIEW

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MRPL28-006
 
MRPL28-008
 
MRPL28-009
 
MRPL28-010
 
MRPL28-011
 
MRPL28-012
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

MRPL28-006 ENSP00000199706
ENST00000199706
Q13084
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Show » Show » 256 30.2 No 0
MRPL28-008 ENSP00000374326
ENST00000389675
Q13084
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Show » Show » 256 30.2 No 0
MRPL28-009 ENSP00000390399
ENST00000447696
Q4TT37
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Show » Show » 218 25.9 No 0
MRPL28-010 ENSP00000398684
ENST00000441883
A2IDC6
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Show » Show » 240 28.5 No 0
MRPL28-011 ENSP00000395305
ENST00000450882
A2IDC7
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Show » Show » 194 23.1 No 0
MRPL28-012 ENSP00000414038
ENST00000429738
A2IDC5
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48 5 No 0