ADD1

GENE INFORMATION

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Gene name

ADD1

Synonyms

Description

adducin 1 (alpha) (HGNC Symbol)

Entrez gene summary

Adducins are a family of cytoskeleton proteins encoded by three genes (alpha, beta, gamma). Adducin is a heterodimeric protein that consists of related subunits, which are produced from distinct genes but share a similar structure. Alpha- and beta-adducin include a protease-resistant N-terminal region and a protease-sensitive, hydrophilic C-terminal region. Alpha- and gamma-adducins are ubiquitously expressed. In contrast, beta-adducin is expressed at high levels in brain and hematopoietic tissues. Adducin binds with high affinity to Ca(2+)/calmodulin and is a substrate for protein kinases A and C. Alternative splicing results in multiple variants encoding distinct isoforms; however, not all variants have been fully described. [provided by RefSeq, Jul 2008]

Chromosome

4 (Chromosome progress)

Cytoband

p16.3

Chromosome location (bp)

2845584 - 2931803

Ensembl

ENSG00000087274 (version 73.37)

Entrez gene

118

UniProt

P35611 (UniProt - Evidence at protein level)

neXtProt

NX_P35611

Antibodypedia

ADD1 antibodies
 

PROTEIN VIEW

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ADD1-001
 
ADD1-002
 
ADD1-003
 
ADD1-009
 
ADD1-010
 
ADD1-011
 
ADD1-013
 
ADD1-014
 
ADD1-015
 
ADD1-022
 
ADD1-023
 
ADD1-201
 
ADD1-202
 
ADD1-203
 
 » 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ADD1-001 ENSP00000381197
ENST00000398129
P35611
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Show » 737 81 No 0
ADD1-002 ENSP00000348100
ENST00000355842
Q86XM2
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Show » 662 73.4 No 0
ADD1-003 ENSP00000381191
ENST00000398123
A2A3N8
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Show » 662 73.3 No 0
ADD1-009 ENSP00000426700
ENST00000508277
D6RF25
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Show » 143 15.9 No 0
ADD1-010 ENSP00000425703
ENST00000510101
D6RJE2
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69 8.1 No 0
ADD1-011 ENSP00000421918
ENST00000511797
D6RAH3
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Show » 137 15.3 No 0
ADD1-013 ENSP00000423024
ENST00000503455
E7ENY0
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Show » 663 73.4 No 0
ADD1-014 ENSP00000421907
ENST00000513328
E7EV99
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Show » 632 70.1 No 0
ADD1-015 ENSP00000424143
ENST00000514940
444 48.4 No 0
ADD1-022 ENSP00000438069
ENST00000536424
H0YFD8
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105 12.1 No 0
ADD1-023 ENSP00000441388
ENST00000541843
114 12.8 No 0
ADD1-201 ENSP00000264758
ENST00000264758
P35611
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Show » 768 84.3 No 0
ADD1-202 ENSP00000381193
ENST00000398125
A2A3N8
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Show » 662 73.3 No 0
ADD1-203 ENSP00000399828
ENST00000446856
P35611
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Show » 737 81 No 0