DNM1L

GENE INFORMATION

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Gene name

DNM1L (HGNC Symbol)

Synonyms

DRP1, DVLP, DYMPLE, HDYNIV, VPS1

Description

dynamin 1-like (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the dynamin superfamily of GTPases. The encoded protein mediates mitochondrial and peroxisomal division, and is involved in developmentally regulated apoptosis and programmed necrosis. Dysfunction of this gene is implicated in several neurological disorders, including Alzheimer's disease. Mutations in this gene are associated with the autosomal dominant disorder, encephalopathy, lethal, due to defective mitochondrial and peroxisomal fission (EMPF). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2013]

Chromosome

12 (Chromosome progress)

Cytoband

p11.21

Chromosome location (bp)

32832134 - 32898486

Ensembl

ENSG00000087470 (version 73.37)

Entrez gene

10059

UniProt

O00429 (UniProt - Evidence at protein level)

neXtProt

NX_O00429

Antibodypedia

DNM1L antibodies
 

PROTEIN VIEW

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 « 
 
DNM1L-001
 
DNM1L-002
 
DNM1L-003
 
DNM1L-004
 
DNM1L-005
 
DNM1L-006
 
DNM1L-007
 
DNM1L-008
 
DNM1L-009
 
DNM1L-010
 
DNM1L-011
 
DNM1L-014
 
DNM1L-015
 
DNM1L-016
 
DNM1L-018
 
DNM1L-023
 
DNM1L-201
 
 » 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

DNM1L-001 ENSP00000415131
ENST00000452533
O00429
Show all »
Show » Show » 710 79.4 No 0
DNM1L-002 ENSP00000449089
ENST00000553257
O00429
Show all »
Show » Show » 749 83.4 No 0
DNM1L-003 ENSP00000450399
ENST00000549701
O00429
Show all »
Show » Show » 736 81.9 No 0
DNM1L-004 ENSP00000350948
ENST00000358214
G8JLD5
Show all »
Show » 712 79.6 No 0
DNM1L-005 ENSP00000266481
ENST00000266481
O00429
Show all »
Show » Show » 699 78.1 No 0
DNM1L-006 ENSP00000390090
ENST00000434676
B4DPZ9
Show all »
Show » 156 17.3 No 0
DNM1L-007 ENSP00000396030
ENST00000413295
B4DDQ3
Show all »
Show » 180 19.9 No 0
DNM1L-008 ENSP00000448610
ENST00000547312
O00429
Show all »
Show » Show » 725 80.5 No 0
DNM1L-009 ENSP00000448936
ENST00000546649
F8VYL3
Show all »
Show » 117 13 No 0
DNM1L-010 ENSP00000370388
ENST00000381000
J3KPI2
Show all »
Show » 738 82.1 No 0
DNM1L-011 ENSP00000448105
ENST00000546757
H0YHY4
Show all »
Show » 54 5.9 No 0
DNM1L-014 ENSP00000450401
ENST00000551643
F8VR28
Show all »
Show » 97 10.5 No 0
DNM1L-015 ENSP00000447845
ENST00000551476
F8VUJ9
Show all »
Show » 172 19.1 No 0
DNM1L-016 ENSP00000447013
ENST00000550154
F8W1W3
Show all »
Show » 169 18.4 No 0
DNM1L-018 ENSP00000447788
ENST00000548750
F8VZ52
Show all »
Show » 261 29 No 0
DNM1L-023 ENSP00000448802
ENST00000547078
48 5.5 No 0
DNM1L-201 ENSP00000404160
ENST00000414834
B4DGC9
Show all »
Show » 533 60 No 0