AURKA

GENE INFORMATION

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Gene name

AURKA (HGNC Symbol)

Synonyms

AIK, ARK1, AurA, BTAK, PPP1R47, STK15, STK6, STK7

Description

aurora kinase A (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a cell cycle-regulated kinase that appears to be involved in microtubule formation and/or stabilization at the spindle pole during chromosome segregation. The encoded protein is found at the centrosome in interphase cells and at the spindle poles in mitosis. This gene may play a role in tumor development and progression. A processed pseudogene of this gene has been found on chromosome 1, and an unprocessed pseudogene has been found on chromosome 10. Multiple transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

Chromosome

20 (Chromosome progress)

Cytoband

q13.2

Chromosome location (bp)

54944445 - 54967393

Ensembl

ENSG00000087586 (version 73.37)

Entrez gene

6790

UniProt

O14965 (UniProt - Evidence at protein level)

neXtProt

NX_O14965

Antibodypedia

AURKA antibodies
 

PROTEIN VIEW

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 « 
 
AURKA-001
 
AURKA-002
 
AURKA-003
 
AURKA-004
 
AURKA-005
 
AURKA-006
 
AURKA-007
 
AURKA-008
 
AURKA-009
 
AURKA-010
 
AURKA-011
 
AURKA-012
 
AURKA-201
 
AURKA-202
 
 » 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

AURKA-001 ENSP00000216911
ENST00000347343
O14965
Show all »
Show » Show » 403 45.8 No 0
AURKA-002 ENSP00000393452
ENST00000441357
Q5QPD4
Show all »
Show » 271 30.7 No 0
AURKA-003 ENSP00000379251
ENST00000395915
O14965
Show all »
Show » Show » 403 45.8 No 0
AURKA-004 ENSP00000321591
ENST00000312783
O14965
Show all »
Show » Show » 403 45.8 No 0
AURKA-005 ENSP00000360407
ENST00000371356
O14965
Show all »
Show » Show » 403 45.8 No 0
AURKA-006 ENSP00000379249
ENST00000395913
O14965
Show all »
Show » Show » 403 45.8 No 0
AURKA-007 ENSP00000405170
ENST00000456249
Q5QPD1
Show all »
Show » 106 11.5 No 0
AURKA-008 ENSP00000405042
ENST00000422322
Q5QPD2
Show all »
Show » 147 16.2 No 0
AURKA-009 ENSP00000388073
ENST00000420474
A3KFJ1
Show all »
Show » 189 21.2 No 0
AURKA-010 ENSP00000379247
ENST00000395911
O14965
Show all »
Show » Show » 403 45.8 No 0
AURKA-011 ENSP00000379243
ENST00000395907
A3KFJ0
Show all »
Show » Show » 347 39.5 No 0
AURKA-012 ENSP00000401358
ENST00000451915
A3KFJ2
Show all »
Show » 79 8.6 No 0
AURKA-201 ENSP00000379245
ENST00000395909
O14965
Show all »
Show » Show » 403 45.8 No 0
AURKA-202 ENSP00000379250
ENST00000395914
O14965
Show all »
Show » Show » 403 45.8 No 0