PPP1R13B

GENERAL INFORMATION

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Gene name

PPP1R13B

Gene description

Protein phosphatase 1, regulatory subunit 13B

Protein class

Plasma proteins
Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

3
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Mixed
GTEx:Expressed in all

Protein evidence

Evidence at protein level

Protein localization

Ubiquitous cytoplasmic and nuclear expression.

ANTIBODY RELIABILITY

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Data reliability
description

Pending RNA-based expert annotation.

Data reliability

Supportive based on 2 antibodies.
HPA006394 , CAB015454
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Mixed

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

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Gene name

PPP1R13B (HGNC Symbol)

Synonyms

ASPP1, KIAA0771, p53BP2-like, p85

Description

Protein phosphatase 1, regulatory subunit 13B (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the ASPP (apoptosis-stimulating protein of p53) family of p53 interacting proteins. The protein contains four ankyrin repeats and an SH3 domain involved in protein-protein interactions. ASPP proteins are required for the induction of apoptosis by p53-family proteins. They promote DNA binding and transactivation of p53-family proteins on the promoters of proapoptotic genes. Expression of this gene is regulated by the E2F transcription factor. [provided by RefSeq, Jul 2008]

Chromosome

14

Cytoband

q32.33

Chromosome location (bp)

103733752 - 103847590

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000088808 (version 78.38)

Entrez gene

23368

UniProt

Q96KQ4 (UniProt - Evidence at protein level)

neXtProt

NX_Q96KQ4

Antibodypedia

PPP1R13B antibodies


PROTEIN BROWSER

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ENST00000202556
 
ENST00000553739
 
ENST00000555734
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PPP1R13B-001 ENSP00000202556
ENST00000202556
Q96KQ4
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Show » Show » 1090 119.6 No 0
PPP1R13B-009 ENSP00000452376
ENST00000555734
G3V5J1
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Show » Show » 149 17.3 No 0
PPP1R13B-010 ENSP00000450734
ENST00000553739
G3V2L3
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Show » Show » 144 16.7 No 0