MRPS33

GENE INFORMATION

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Gene name

MRPS33 (HGNC Symbol)

Synonyms

CGI-139

Description

mitochondrial ribosomal protein S33 (HGNC Symbol)

Entrez gene summary

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. The 28S subunit of the mammalian mitoribosome may play a crucial and characteristic role in translation initiation. This gene encodes a 28S subunit protein that is one of the more highly conserved mitochondrial ribosomal proteins among mammals, Drosophila and C. elegans. Splice variants that differ in the 5' UTR have been found for this gene; all variants encode the same protein. Pseudogenes corresponding to this gene are found on chromosomes 1q, 4p, 4q, and 20q [provided by RefSeq, Jul 2008]

Chromosome

7 (Chromosome progress)

Cytoband

q34

Chromosome location (bp)

140705854 - 140715028

Ensembl

ENSG00000090263 (version 73.37)

Entrez gene

51650

UniProt

Q9Y291 (UniProt - Evidence at protein level)

neXtProt

NX_Q9Y291

Antibodypedia

MRPS33 antibodies
 

PROTEIN VIEW

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MRPS33-001
 
MRPS33-002
 
MRPS33-003
 
MRPS33-008
 
MRPS33-009
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

MRPS33-001 ENSP00000320567
ENST00000324787
Q9Y291
Show all »
Show » 106 12.6 No 0
MRPS33-002 ENSP00000376732
ENST00000393008
Q9Y291
Show all »
Show » 106 12.6 No 0
MRPS33-003 ENSP00000420709
ENST00000467334
C9JBY7
Show all »
Show » 96 11.5 No 0
MRPS33-008 ENSP00000418451
ENST00000496958
Q9Y291
Show all »
Show » 106 12.6 No 0
MRPS33-009 ENSP00000417287
ENST00000469351
Q9Y291
Show all »
Show » 106 12.6 No 0