AARS

GENE INFORMATION

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Gene name

AARS

Synonyms

Description

alanyl-tRNA synthetase (HGNC Symbol)

Entrez gene summary

The human alanyl-tRNA synthetase (AARS) belongs to a family of tRNA synthases, of the class II enzymes. Class II tRNA synthases evolved early in evolution and are highly conserved. This is reflected by the fact that 498 of the 968-residue polypeptide human AARS shares 41% identity witht the E.coli protein. tRNA synthases are the enzymes that interpret the RNA code and attach specific aminoacids to the tRNAs that contain the cognate trinucleotide anticodons. They consist of a catalytic domain which interacts with the amino acid acceptor-T psi C helix of the tRNA, and a second domain which interacts with the rest of the tRNA structure. [provided by RefSeq, Jul 2008]

Chromosome

16 (Chromosome progress)

Cytoband

q22.1

Chromosome location (bp)

70286198 - 70323446

Ensembl

ENSG00000090861 (version 73.37)

Entrez gene

16

UniProt

P49588 (UniProt - Evidence at protein level)

neXtProt

NX_P49588

Antibodypedia

AARS antibodies
 

PROTEIN VIEW

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AARS-001
 
AARS-005
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

AARS-001 ENSP00000261772
ENST00000261772
P49588
Show all »
Show » Show » 968 106.8 No 0
AARS-005 ENSP00000455360
ENST00000565361
Show » 280 30.1 No 0