DLD

GENE INFORMATION

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Gene name

DLD (HGNC Symbol)

Synonyms

DLDH, GCSL, LAD

Description

dihydrolipoamide dehydrogenase (HGNC Symbol)

Entrez gene summary

This gene encodes the L protein of the mitochondrial glycine cleavage system. The L protein, also named dihydrolipoamide dehydrogenase, is also a component of the pyruvate dehydrogenase complex, the alpha-ketoglutarate dehydrogenase complex, and the branched-chain alpha-keto acide dehydrogenase complex. Mutations in this gene have been identified in patients with E3-deficient maple syrup urine disease and lipoamide dehydrogenase deficiency. [provided by RefSeq, Jul 2008]

Chromosome

7 (Chromosome progress)

Cytoband

q31.1

Chromosome location (bp)

107531415 - 107572175

Ensembl

ENSG00000091140 (version 73.37)

Entrez gene

1738

UniProt

P09622 (UniProt - Evidence at protein level)

neXtProt

NX_P09622

Antibodypedia

DLD antibodies
 

PROTEIN VIEW

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DLD-001
 
DLD-002
 
DLD-003
 
DLD-004
 
DLD-005
 
DLD-006
 
DLD-013
 
DLD-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

DLD-001 ENSP00000205402
ENST00000205402
P09622
Show all »
Show » Show » 509 54.2 No 0
DLD-002 ENSP00000402593
ENST00000415325
F8WDY5
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58 6.7 No 0
DLD-003 ENSP00000417016
ENST00000440410
E9PEX6
Show all »
Show » Show » 486 51.8 No 0
DLD-004 ENSP00000388077
ENST00000451081
F2Z2E3
Show all »
Show » 115 12.3 No 0
DLD-005 ENSP00000387542
ENST00000437604
B4DT69
Show all »
Show » Show » 461 49.3 No 0
DLD-006 ENSP00000390667
ENST00000417551
P09622
Show all »
Show » Show » 509 54.2 No 0
DLD-013 ENSP00000409590
ENST00000450038
F8WDM5
Show all »
Show » Show » 114 12.2 No 0
DLD-201 ENSP00000442399
ENST00000537148
B4DHG0
Show all »
Show » Show » 410 43.6 No 0