WDR7

GENE INFORMATION

? »

Gene name

WDR7 (HGNC Symbol)

Synonyms

KIAA0541, TRAG

Description

WD repeat domain 7 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD) that may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. The encoded protein forms the beta subunit of rabconnectin-3 and binds directly with Rab3A GDP/GTP exchange protein and indirectly with Rab3A GDP/GTP activating protein; these proteins are regulators of Rab3 small G protein family members involved in control of the calcium-dependant exocytosis of neurotransmitters. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]

Chromosome

18 (Chromosome progress)

Cytoband

q21.31

Chromosome location (bp)

54318574 - 54698828

Ensembl

ENSG00000091157 (version 73.37)

Entrez gene

23335

UniProt

Q9Y4E6 (UniProt - Evidence at protein level)

neXtProt

NX_Q9Y4E6

Antibodypedia

WDR7 antibodies
 

PROTEIN VIEW

? »
 
 
 
WDR7-001
 
WDR7-002
 
WDR7-003
 
WDR7-005
 
WDR7-006
 
WDR7-007
 
WDR7-009
 
WDR7-010
 
WDR7-011
 
WDR7-012
 
 
 
 
 

PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

WDR7-001 ENSP00000254442
ENST00000254442
Q9Y4E6
Show all »
Show » Show » 1490 163.8 No 0
WDR7-002 ENSP00000350187
ENST00000357574
Q9Y4E6
Show all »
Show » 1457 160.5 No 0
WDR7-003 ENSP00000466438
ENST00000593058
K7EMB8
Show all »
Show » 169 18.4 No 0
WDR7-005 ENSP00000467644
ENST00000590557
K7EQ29
Show all »
176 19 No 0
WDR7-006 ENSP00000466288
ENST00000587403
K7ELZ4
Show all »
104 11.2 No 0
WDR7-007 ENSP00000468357
ENST00000585824
K7ERP9
Show all »
320 35 No 0
WDR7-009 ENSP00000468555
ENST00000586124
190 20.5 No 0
WDR7-010 ENSP00000467596
ENST00000591449
62 6.7 No 0
WDR7-011 ENSP00000466480
ENST00000585669
40 4.5 No 0
WDR7-012 ENSP00000467485
ENST00000589935
K7EPQ4
Show all »
67 7.4 No 0