ANGPT2

GENE INFORMATION

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Gene name

ANGPT2 (HGNC Symbol)

Synonyms

Ang2

Description

angiopoietin 2 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is an antagonist of angiopoietin 1 (ANGPT1) and endothelial TEK tyrosine kinase (TIE-2, TEK). The encoded protein disrupts the vascular remodeling ability of ANGPT1 and may induce endothelial cell apoptosis. Three transcript variants encoding three different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Chromosome

8 (Chromosome progress)

Cytoband

p23.1

Chromosome location (bp)

6357172 - 6420930

Ensembl

ENSG00000091879 (version 73.37)

Entrez gene

285

UniProt

O15123 (UniProt - Evidence at protein level)

neXtProt

NX_O15123

Antibodypedia

ANGPT2 antibodies
 

PROTEIN VIEW

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ANGPT2-001
 
ANGPT2-002
 
ANGPT2-003
 
ANGPT2-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ANGPT2-001 ENSP00000314897
ENST00000325203
O15123
Show all »
Show » Show » 496 56.9 Yes 0
ANGPT2-002 ENSP00000343517
ENST00000338312
O15123
Show all »
Show » Show » 444 51 Yes 0
ANGPT2-003 ENSP00000428023
ENST00000523120
E7EVQ3
Show all »
459 52.6 Yes 0
ANGPT2-201 ENSP00000400782
ENST00000415216
O15123
Show all »
Show » Show » 495 56.8 Yes 0