TRPM7

GENE INFORMATION

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Gene name

TRPM7 (HGNC Symbol)

Synonyms

CHAK1, LTRPC7, TRP-PLIK

Description

Transient receptor potential cation channel, subfamily M, member 7 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is both an ion channel and a serine/threonine protein kinase. The kinase activity is essential for the ion channel function, which serves to increase intracellular calcium levels and to help regulate magnesium ion homeostasis. Defects in this gene are a cause of amyotrophic lateral sclerosis-parkinsonism/dementia complex of Guam.[provided by RefSeq, May 2010]

Chromosome

15

Cytoband

q21.2

Chromosome location (bp)

50844670 - 50979012

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000092439 (version 75.37)

Entrez gene

54822

UniProt

Q96QT4 (UniProt - Evidence at protein level)

neXtProt

NX_Q96QT4

Antibodypedia

TRPM7 antibodies
 

PROTEIN VIEW

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TRPM7-001
 
TRPM7-002
 
TRPM7-004
 
TRPM7-010
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

TRPM7-001 ENSP00000320239
ENST00000313478
Q96QT4
Show all »
Show » Show » 1865 212.7 No 6
TRPM7-002 ENSP00000453277
ENST00000560955
H0YLN8
Show all »
Show » Show » 1864 212.6 No 6
TRPM7-004 ENSP00000452873
ENST00000560638
Q96QT4
Show all »
Show » Show » 535 62.7 No 5
TRPM7-010 ENSP00000454066
ENST00000561267
Show » Show » 234 26.8 No 0