TYRO3

GENE INFORMATION

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Gene name

TYRO3 (HGNC Symbol)

Synonyms

Brt, Dtk, RSE, Sky, Tif

Description

TYRO3 protein tyrosine kinase (HGNC Symbol)

Entrez gene summary

The gene is part of a 3-member transmembrane receptor kinase receptor family with a processed pseudogene distal on chromosome 15. The encoded protein is activated by the products of the growth arrest-specific gene 6 and protein S genes and is involved in controlling cell survival and proliferation, spermatogenesis, immunoregulation and phagocytosis. The encoded protein has also been identified as a cell entry factor for Ebola and Marburg viruses. [provided by RefSeq, May 2010]

Chromosome

15 (Chromosome progress)

Cytoband

q15.1

Chromosome location (bp)

41849873 - 41871536

Ensembl

ENSG00000092445 (version 73.37)

Entrez gene

7301

UniProt

Q06418 (UniProt - Evidence at protein level)

neXtProt

NX_Q06418

Antibodypedia

TYRO3 antibodies
 

PROTEIN VIEW

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TYRO3-001
 
TYRO3-002
 
TYRO3-006
 
TYRO3-008
 
TYRO3-010
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

TYRO3-001 ENSP00000263798
ENST00000263798
Q06418
Show all »
Show » Show » 890 96.9 Yes 1
TYRO3-002 ENSP00000454050
ENST00000559066
H0YNK6
Show all »
Show » Show » 845 92.3 No 1
TYRO3-006 ENSP00000453835
ENST00000559815
Show » 121 13 No 0
TYRO3-008 ENSP00000452995
ENST00000559851
H0YKZ2
Show all »
21 2.2 No 0
TYRO3-010 ENSP00000455441
ENST00000568343
Show » Show » 286 32.2 No 0