CAPN3

GENE INFORMATION

? »

Gene name

CAPN3 (HGNC Symbol)

Synonyms

CANP3, LGMD2, LGMD2A, nCL-1, p94

Description

calpain 3, (p94) (HGNC Symbol)

Entrez gene summary

Calpain, a heterodimer consisting of a large and a small subunit, is a major intracellular protease, although its function has not been well established. This gene encodes a muscle-specific member of the calpain large subunit family that specifically binds to titin. Mutations in this gene are associated with limb-girdle muscular dystrophies type 2A. Alternate promoters and alternative splicing result in multiple transcript variants encoding different isoforms and some variants are ubiquitously expressed. [provided by RefSeq, Jul 2008]

Chromosome

15 (Chromosome progress)

Cytoband

q15.1

Chromosome location (bp)

42640301 - 42704516

Ensembl

ENSG00000092529 (version 73.37)

Entrez gene

825

UniProt

P20807 (UniProt - Evidence at protein level)

neXtProt

NX_P20807

Antibodypedia

CAPN3 antibodies
 

PROTEIN VIEW

? »
 
 
 « 
 
CAPN3-005
 
CAPN3-006
 
CAPN3-007
 
CAPN3-008
 
CAPN3-009
 
CAPN3-010
 
CAPN3-011
 
CAPN3-012
 
CAPN3-013
 
CAPN3-015
 
CAPN3-017
 
CAPN3-018
 
CAPN3-019
 
CAPN3-021
 
CAPN3-022
 
CAPN3-201
 
CAPN3-202
 
 » 
 
 
 
 

PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CAPN3-005 ENSP00000183936
ENST00000349748
P20807
Show all »
Show » Show » 729 84.1 No 0
CAPN3-006 ENSP00000336840
ENST00000337571
P20807
Show all »
Show » Show » 156 18.2 No 0
CAPN3-007 ENSP00000380384
ENST00000397200
P20807
Show all »
Show » Show » 309 35.9 No 0
CAPN3-008 ENSP00000350181
ENST00000357568
P20807
Show all »
Show » Show » 815 93.5 No 0
CAPN3-009 ENSP00000380349
ENST00000397163
P20807
Show all »
Show » Show » 821 94.3 No 0
CAPN3-010 ENSP00000454379
ENST00000569827
H3BMH1
Show all »
Show » 256 29.9 No 0
CAPN3-011 ENSP00000456607
ENST00000567071
188 21.5 No 0
CAPN3-012 ENSP00000380387
ENST00000397204
P20807
Show all »
Show » Show » 156 18.2 No 0
CAPN3-013 ENSP00000456575
ENST00000561817
H3BS77
Show all »
Show » 191 22 No 0
CAPN3-015 ENSP00000455254
ENST00000569136
P20807
Show all »
Show » Show » 156 18.2 No 0
CAPN3-017 ENSP00000457878
ENST00000565559
H3BUZ3
Show all »
Show » 157 17.6 No 0
CAPN3-018 ENSP00000457759
ENST00000565274
H3BUR3
Show all »
Show » 110 12.4 No 0
CAPN3-019 ENSP00000457898
ENST00000564503
Show » 169 19.5 No 0
CAPN3-021 ENSP00000456514
ENST00000567817
H3BS30
Show all »
Show » 93 11 No 0
CAPN3-022 ENSP00000454937
ENST00000568153
Show » 67 7.9 No 0
CAPN3-201 ENSP00000326281
ENST00000318023
F8W8F5
Show all »
Show » Show » 815 93.5 No 0
CAPN3-202 ENSP00000348667
ENST00000356316
C6EVS3
Show all »
Show » Show » 728 84.1 No 0